Search
Close this search box.

We are creating some awesome events for you. Kindly bear with us.

Research by Hong Kong scientists may bring safer and more affordable chiral medicine

Research by Hong Kong scientists may bring safer and more affordable chiral medicine

According to recent press release, a research team from the Hong Kong University of Science and Technology (HKUST) has discovered a new way to produce chiral molecules in a more efficient and eco-friendly way.

Currently, over half of the approved drugs in use in the world are chiral, which treats a wide range of conditions including cardiovascular, respiratory and gastrointestinal diseases.

Last year, more than two thirds of the newly developing drugs are made of chiral molecules. Many chiral drugs are top sellers, including high-cholesterol medicine Lipitor, and antibiotic Amoxicillin.

The market for chiral drugs is a fast growing one, with the market size jumping nearly four folds to around US$800 billion over the past decade and still growing.

However, the production of chiral drugs is difficult and costly as the production process is complicated and requires rare and expensive raw materials in general.

A team led by Prof Jianwei Sun, Associate Professor of the HKUST Department of Chemistry, discovered useful methods that could result in a more efficient and affordable production of the drugs.

“Chiral molecules contain subunits which are like twin brothers, they have extremely similar, mirror-like architecture but may exhibit distinct traits in our body. These ‘twin components’ are particularly hard to separate, and it is costly to get just the useful part out of the two, Chiral allenes represents an example of this type which were made by the very expensive chiral raw materials,” said Prof Sun.

However, Prof Sun’s team has discovered that chiral allenes can be produced through organic catalysis using racemic propargylic alcohols, which is cheap and available. The catalyst is also recyclable and reusable without having to create metal wastes.

According to Prof Sun, the new method is not only more economical and friendly to the environment, such green catalysis could also have profound impact in health care as drug companies may be able to create and develop chiral drugs in a cheaper and more sustainable way.

The findings were recently published in Nature Communications.

PARTNER

Qlik’s vision is a data-literate world, where everyone can use data and analytics to improve decision-making and solve their most challenging problems. A private company, Qlik offers real-time data integration and analytics solutions, powered by Qlik Cloud, to close the gaps between data, insights and action. By transforming data into Active Intelligence, businesses can drive better decisions, improve revenue and profitability, and optimize customer relationships. Qlik serves more than 38,000 active customers in over 100 countries.

PARTNER

As a Titanium Black Partner of Dell Technologies, CTC Global Singapore boasts unparalleled access to resources.

Established in 1972, we bring 52 years of experience to the table, solidifying our position as a leading IT solutions provider in Singapore. With over 300 qualified IT professionals, we are dedicated to delivering integrated solutions that empower your organization in key areas such as Automation & AI, Cyber Security, App Modernization & Data Analytics, Enterprise Cloud Infrastructure, Workplace Modernization and Professional Services.

Renowned for our consulting expertise and delivering expert IT solutions, CTC Global Singapore has become the preferred IT outsourcing partner for businesses across Singapore.

PARTNER

Planview has one mission: to build the future of connected work. Our solutions enable organizations to connect the business from ideas to impact, empowering companies to accelerate the achievement of what matters most. Planview’s full spectrum of Portfolio Management and Work Management solutions creates an organizational focus on the strategic outcomes that matter and empowers teams to deliver their best work, no matter how they work. The comprehensive Planview platform and enterprise success model enables customers to deliver innovative, competitive products, services, and customer experiences. Headquartered in Austin, Texas, with locations around the world, Planview has more than 1,300 employees supporting 4,500 customers and 2.6 million users worldwide. For more information, visit www.planview.com.

SUPPORTING ORGANISATION

SIRIM is a premier industrial research and technology organisation in Malaysia, wholly-owned by the Minister​ of Finance Incorporated. With over forty years of experience and expertise, SIRIM is mandated as the machinery for research and technology development, and the national champion of quality. SIRIM has always played a major role in the development of the country’s private sector. By tapping into our expertise and knowledge base, we focus on developing new technologies and improvements in the manufacturing, technology and services sectors. We nurture Small Medium Enterprises (SME) growth with solutions for technology penetration and upgrading, making it an ideal technology partner for SMEs.

PARTNER

HashiCorp provides infrastructure automation software for multi-cloud environments, enabling enterprises to unlock a common cloud operating model to provision, secure, connect, and run any application on any infrastructure. HashiCorp tools allow organizations to deliver applications faster by helping enterprises transition from manual processes and ITIL practices to self-service automation and DevOps practices. 

PARTNER

IBM is a leading global hybrid cloud and AI, and business services provider. We help clients in more than 175 countries capitalize on insights from their data, streamline business processes, reduce costs and gain the competitive edge in their industries. Nearly 3,000 government and corporate entities in critical infrastructure areas such as financial services, telecommunications and healthcare rely on IBM’s hybrid cloud platform and Red Hat OpenShift to affect their digital transformations quickly, efficiently and securely. IBM’s breakthrough innovations in AI, quantum computing, industry-specific cloud solutions and business services deliver open and flexible options to our clients. All of this is backed by IBM’s legendary commitment to trust, transparency, responsibility, inclusivity and service.