Singapore's sovereign wealth fund GIC recently announced
that it has invested in Oxford Nanopore Technologies.
is the developer of the world's only portable, scalable, real-time deoxyribonucleic
acid (DNA)/ribonucleic acid (RNA) sequencer, with a customer base spanning over
Oxford Nanopore’s innovation, the MinION, is a portable,
real-time, long-read, low-cost device that has been designed to bring easy
biological analyses to anyone, whether in scientific research, education or a
range of real-world applications such as disease and/or pathogen surveillance,
environmental monitoring, food-chain surveillance, self-quantification or even
According to Oxford Nanopore, nanopore sequencing is being applied to fields where
portability, ease of set up, long reads and real-time analysis make a
difference and where users want to control the time-to-results.
GIC is one of the key investors in ONT’s £100-million
(equivalent to S$184 million) capital raising. Other investors include China
Construction Bank International (CCBI), Australian hospitality industry pension
fund HostPlus and existing investors of ONT.
“I’m pleased that
such a pioneering British business has obtained the investment they need to
grow, creating thousands more jobs and continuing ground-breaking research in
this field here in the UK. Through our modern Industrial Strategy, we are
making sure that Britain remains the natural choice for innovative firms to
prosper – investing in the future of our country,’ said Prime Minister
of the UK Theresa May.
The funds raised will be used to support a new high-volume,
high-tech manufacturing facility, commercial expansion and the development of
new innovative products.
According to a press
release by Oxford Nanopore, the funds raised will also support research and
development (R&D) as Oxford Nanopore expands its suite of nanopore analysis
devices. The currently available pocket MinION and desktop GridION are being joined by high-throughput modular
sequencing with PromethION and small,
single-test sequencing with Flongle.
“Oxford Nanopore has a unique business model of providing
accessible, real-time DNA analysis technologies that can be applied to pocket-sized
or industrial installations,” said GIC’s Chief Investment Officer of Public
Equities Bryan Yeo.
“We believe this will continue to drive growth in their user
base as well as in new applications for DNA or RNA sequencing. This investment
reflects our confidence in the global demand outlook for DNA information across
many industries over the long term,” he added.
Headquartered at the Oxford Science Park outside
Oxford in the UK, Oxford Nanopore has a commercial presence in US, China,
Japan, France, and Germany. New operations are now being opened in Shanghai and
San Francisco. It has also announced the forthcoming construction of a new
bespoke 34,000sqft manufacturing facility on the Harwell Science and Innovation
Rehabilitation services have gained increasing significance, as highlighted by Deputy Prime Minister Heng Swee Keat during RehabWeek 2023. The demand for rehab services is growing worldwide due to an ageing population and a rising incidence of chronic diseases. To meet this demand and improve outcomes, the field of rehabilitation is embracing innovation, particularly through advancements in technology, robotics, and digitalisation.
Rehabilitation plays a crucial role in enabling individuals, regardless of age, to regain independence and participate meaningfully in daily life. With the World Health Organisation estimating that 1 in 3 people globally may benefit from rehab services, the importance of this field cannot be overstated.
Beyond individual well-being, rehabilitation contributes to productive longevity and reduces downstream medical costs when integrated into holistic care plans. Thus, it aligns with the United Nations Sustainable Development Goal of “healthy lives and well-being for all at all ages.”
Deputy Prime Minister Heng shared his personal experience as a stroke survivor, emphasising the pivotal role that therapists and early rehabilitation played in his recovery journey. Early rehab interventions were instrumental in mitigating the debilitating effects of extended bed rest in the ICU. Dedicated therapists, combined with intensive rehab, enabled him to regain full functionality, underscoring the transformative potential of rehabilitation services.
Innovations in rehabilitation leverage broader trends like robotics and digitalisation. These innovations offer precision rehabilitation, tailoring treatment plans to individual needs. They also mitigate manpower constraints by augmenting human efforts with technology.
For instance, robotics-assisted physiotherapy and games-based cognitive exercises are becoming increasingly prevalent. Moreover, virtual rehabilitation has gained prominence during the COVID-19 pandemic, enhancing convenience and empowering patients to take charge of their rehab journeys from home.
Many societies are facing the dual challenge of an ageing population and a declining workforce to provide rehabilitation services. Technology is critical in augmenting these efforts to meet growing demand. Innovations in rehabilitation enhance its effectiveness and accessibility, ensuring that patients follow through with and benefit from rehab programs.
Singapore is at the forefront of innovative rehabilitation practices. Its acute hospitals offer excellent rehab care services and conduct research to improve care. Notably, Tan Tock Seng Hospital is a pioneer in rehabilitation medicine. Changi General Hospital houses the Centre for Healthcare Assistive and Robotics Technology (CHART), facilitating the synergy between clinical needs and technological innovation.
The One-Rehab Framework is a recent innovation in Singapore, ensuring timely access to rehabilitation care. This framework enables seamless care coordination across different settings and care team members through a common IT portal and harmonised clinical outcomes. It streamlines the sharing of relevant patient information and encourages right-siting of care within the community, reducing the burden on acute hospitals.
According to Deputy Prime Minister Heng, RehabWeek serves as a platform for delegates with diverse expertise and a shared commitment to advancing rehabilitation care. It encourages the sharing of best practices and useful technologies to strengthen collective impact, especially when addressing global challenges.
Singapore stands ready to collaborate with international partners, offering its strong ecosystem in research, innovation, and enterprise to advance the field of rehabilitation for the benefit of people worldwide.
He added that rehabilitation is evolving and embracing technological innovations to meet the increasing demand for its services, especially in ageing societies. “Collaboration, innovation, and a focus on the last-mile delivery of care are crucial for ensuring that individuals can live well and maximise their potential through effective rehabilitation,” Deputy Prime Minister Heng said. “Singapore’s commitment to these principles makes it a valuable partner in advancing the frontiers of rehabilitation on a global scale.”
The Vietnamese government has said that digital transformation and green transformation are inevitable global trends. They have a crucial role in enhancing economic growth, labour productivity, competitiveness, production, and business efficiency. They also reduce reliance on fuel sources that cause pollution and minimise carbon footprint.
To discuss digital and green transformation for sustainable development and to foster networking opportunities for businesses to accelerate their green transitions, the Ministry of Science and Technology held a forum in the northern province of Quang Ninh.
Domestic and international scientists, along with representatives from organisations and technology companies, deliberated on strategies to speed up green and digital transformations. They underscored the importance of advancing technological innovation and implementing reforms in human resource management, training, and quality enhancement to create new products and processes. This, in turn, will boost business value, aid in the delivery of better goods and services to society, and expedite Vietnam’s industrialisation and modernisation processes.
Participants suggested the establishment of a support mechanism for industries implementing green and digital transformation solutions in Vietnamese businesses. They also stressed that it is necessary to promote Horizon Europe’s international cooperation programme on joint research and innovation for Vietnam and have comprehensive digital transformation solutions for businesses.
During the forum, Quang Ninh province representatives, the Vietnam Union of Science and Technology Associations (VUSTA), businesses, and organisations exchanged memoranda of understanding regarding collaboration in the domains of digital transformation and green transformation.
Vietnam has been introducing emerging technologies in the agricultural sector to promote sustainable growth. Earlier this year, the government announced plans to introduce artificial intelligence (AI) for the optimisation of farming practices, including weather prediction, monitoring of plant and livestock health, and enhancing product quality.
AI can improve crop productivity and help control pests, diseases, and cultivation conditions. It can improve the performance of farming-related tasks across food supply chains. Advancements in the manufacturing of AI-controlled robots are assisting farmers worldwide in utilising less land and labour while simultaneously boosting production output.
Vietnam’s commitment to technological advancements in agriculture extends beyond AI, as highlighted by the government’s plans to harness biotechnology. In September, the Politburo issued a resolution under which Vietnam aims to be among the top ten Asian countries in biotechnology production and services by 2030.
As OpenGov Asia reported, the biotechnology sector is on the verge of becoming a significant economic and technological industry, with an expected 50% rise in the number of companies in terms of investment size and growth rate. Additionally, it is projected that half of the imported biotechnology products will be substituted by domestic production. This sector is anticipated to make a 7% contribution to the Gross Domestic Product (GDP).
Vietnam aims to establish a thriving biotechnology sector by 2045, positioning itself as a prominent centre for smart production, services, biotechnology startups, and innovation in Asia. This sector is expected to contribute 10% to 15% to the GDP by that year.
As a result of its tropical climate and its economic shift away from agriculture, biotechnology plays a vital role in Vietnam’s industrialisation and modernisation efforts. It contributes significantly to ensuring food security, facilitating economic restructuring, and promoting sustainable development. Furthermore, in environmental conservation, biotechnology has brought forth numerous solutions. These include the breakdown of inorganic and organic pollutants, waste treatment, industrial waste processing, and the use of microorganisms to address oil spills and incidents of oil contamination.
Vietnam can focus on developing various aspects within the biotechnology sector, such as agricultural advancements in crop and animal breeding, manufacturing veterinary drugs, developing vaccines, and creating bio-fertilizers.
Defence Minister Rajnath Singh has inaugurated several digital projects for the Defence Accounts Department (DAD) as part of its 276th Annual Day celebrations. The initiatives include:
The Summary of Accounts, Budget, and Expenditure for Raksha Mantralaya (the Ministry of Defence) tool aims to provide a more accurate and objective view of defence financial information like payment, accounting, and budgeting in India.
This analytics tool integrates, compiles, sanitises, and standardises financial data from various applications, data sources, and databases. It then offers a real-time, comprehensive platform with dashboard features, allowing users to visualise trends, display metrics, present graphs illustrating key performance indicators, and generate reports, among other functionalities.
SARANSH will function as a complete dashboard for higher management, offering a quick overview of all defence expenditures. It enables centralised monitoring and encourages data-driven decision-making for all defence organisations.
The Bill Information and Work Analysis System will function as a dashboard for various Principal Controllers of Defence Accounts (PCsDA)/ Controllers of Defence Accounts (CsDA), providing different infographics to monitor and analyse the whole process flow of bill management. It will also generate reports on Key Performance Indicators (KPIs). It provides real-time detailed analyses of bill processing, with interactive visualisations of granular data flowing through the various office automation systems within a controller office.
E-Raksha Awaas is a centralised and comprehensive software package designed to enhance and streamline the process of generating rent and related charges for rentable buildings within Defence Services. It also facilitates the prompt remission of these charges to government accounts. This package acts as a unified online platform for all stakeholders engaged in the generation, recovery, and remission of rent and allied charges.
Minister Singh described the DAD as the guardian of defence finance and commended its efforts to strengthen the country’s defence capabilities through transparent and efficient systems, praising its prudent resource management and output optimisation.
He suggested ways to improve the department’s efficiency such as encouraging DAD officials to enhance their professional skills to address the challenges posed by “constantly evolving times”. He urged them to partner with organisations like the Indian Institutes of Management (IIMs) and the Institute of Chartered Accountants of India (ICAI) to create and implement customised training modules, as per requirements.
Providing financial advice is one of the DAD’s most crucial responsibilities, the Minister noted. The DAD should consider two key aspects when offering financial advice: a realistic assessment of the demands of the user agency and a thorough understanding of the product’s market.
He explained that it is important to evaluate whether there is a need to purchase a product and whether a similar product of equal or greater effectiveness is available in the market at a lower cost. This understanding will enhance the quality of financial advice.
Furthermore, to foster such an understanding, Singh suggested establishing an in-house mechanism—a standing committee of experienced individuals who can research and analyse market forces and offer valuable insights to field officers. “Big banks and financial institutions develop in-house economic intelligence and research teams. On similar lines, the DAD needs to develop an in-house team for market research and intelligence,” he stated.
It is also vital to strengthen the internal vigilance mechanism to detect and review suspicious activity. This will not only expedite addressing issues but also enhance public trust in the department, the Minister said.
Scientists from Washington University in St. Louis have created a sonobiopsy method to diagnose brain disease. The Sonobiopsy method employs ultrasound and microbubbles to momentarily breach the barrier, enabling brain RNA, DNA, and proteins to enter the bloodstream for analysis. While this technique was initially tested on animals, a recent study demonstrates its safety and viability for human use. This innovation may pave the way for non-invasive brain disease and tumour diagnostics.
Eric Leuthardt, MD, co-senior author and co-inventor of the technology, stated that Magnetic Resonance Imaging (MRI) drastically transformed brain disease diagnosis in the 1980s and ’90s, offering structural and functional brain imaging capabilities.
Leuthardt, the Shi Hui Huang Professor of Neurosurgery and a professor of neuroscience at the School of Medicine in biomedical engineering and mechanical engineering at the McKelvey School of Engineering referred to sonobiopsy as the third revolution, emphasising its molecular aspect. This innovative technique allows blood sample collection reflecting gene expression and molecular characteristics at the brain lesion site, essentially performing a brain biopsy without the associated risks of surgery.
Eric Leuthardt and Hong Chen, PhD, Associate Professors of Biomedical Engineering at McKelvey Engineering and Neurosurgery at the School of Medicine, developed the groundbreaking technique, focusing on multidisciplinary research to create engineered solutions for neurological diseases.
The technique employs focused ultrasound to target a brain lesion at a millimetre scale. Subsequently, microbubbles are injected into the bloodstream, travelling to the designated area and bursting, creating minuscule, temporary openings in the blood-brain barrier. These openings naturally close within a few hours, causing no lasting harm. Within this time frame, brain lesion biomolecules can exit the bloodstream, facilitating their collection through a standard blood draw.
Hong Chen, another Senior Co-author and co-inventor of the technology described this innovation as initiating a new field for brain-related conditions. It offers the capability to noninvasively and nondestructively access all brain regions, enabling the retrieval of genetic information about tumours before surgical procedures.
This information aids neurosurgeons in determining the best approach to surgery, helping confirm the nature of suspicious findings on imaging. Furthermore, it paves the way for studying diseases that typically don’t undergo surgical biopsies, including neurodevelopmental, neurodegenerative, and psychiatric disorders.
Initially, the researchers utilised a commercially available ultrasound device combined with an MRI scanner, a setup limited by cost and MRI availability. To streamline the procedure, Hong Chen’s team designed a portable, handheld ultrasound probe that could be attached to a stereotactic pointer commonly used by neurosurgeons for pinpointing brain lesions. This device was seamlessly integrated into the clinical workflow, requiring no additional training for neurosurgeons.
Eric Leuthardt emphasised the user-friendliness of this device, stating that it was efficiently utilised during the study in the operating room but could also be employed in a clinic or at a patient’s bedside in a hospital. He noted that this approach was a significant step toward making advanced diagnostics more accessible, enabling the examination of patients’ brains without needing a high-tech, multimillion-dollar scanner.
In their research, the team conducted sonobiopsies on five individuals with brain tumours using this device. Subsequently, the tumours were removed surgically following the standard care protocol.
The analysis of blood samples collected before and after sonication revealed that the technique increased circulating tumour DNA, ranging from 1.6-fold to 5.6-fold, depending on the specific type of DNA examined.
Circulating tumour DNA holds crucial information about genetic alterations in a patient’s tumour, which guides treatment decisions regarding the tumour’s aggressiveness. Notably, the procedure showed no signs of causing damage to brain tissue, affirming its safety.
A collaboration in science and technology has emerged as the Ministry of Higher Education, Science, Research, and Innovation of Thailand (MHESI) joined forces with the Ministry of Science and Technology (MOST) of the People’s Republic of China. The two nations came together to review the progress of ongoing collaborative projects and chart a course for future technological innovations.
The meeting was attended by figures in the field of science and technology, including Prof Dr Sirirurg Songsivilai, Permanent Secretary of MHESI, and Mr Zhang Guang Jun, Deputy Minister of MOST. Notably, Executive Vice President Dr Uracha Ruktanonchai represented the National Science and Technology Development Agency (NSTDA), underlining the significance of the collaboration.
One of the projects under this collaborative effort is centred around rail technology. It combines the expertise of the Rail and Modern Transport Research Centre of NSTDA, the Thailand Institute of Scientific and Technological Research (TISTR), and the China Railway Company. Their goal is to establish the China-Thailand Belt and Road Joint Laboratory on Rail Transit.
Public transportation is vital to modern urban life, shaping how people move within cities, reducing traffic congestion, and minimising the environmental footprint. As Thailand and China embark on collaborative endeavours in rail technology, they contribute to enhancing public transportation systems, which stand as a cornerstone of sustainable mobility.
This laboratory will be a hub for cutting-edge research and testing on rail transit systems. With Thailand’s high-speed train project on the horizon, this laboratory is poised to play a crucial role in ensuring its successful implementation.
The Thailand-China Technology Transfer Centre (TCTTC), a collaborative initiative led by NSTDA, represents another milestone in this partnership. TCTTC has fostered collaboration by facilitating researcher exchanges, supporting training programmes, and enabling business matching between Thai and Chinese enterprises. These initiatives have yielded positive outcomes for both nations.
As the collaboration looks ahead to 2024, TCTTC has set its sights on ramping up technology transfer activities in several key areas. Notably, the focus will be on digital technology, artificial intelligence (AI), and technologies. These forward-looking endeavours are driven by a shared commitment to addressing the United Nations Sustainable Development Goals (SDGs) and leveraging innovation for sustainable growth and development.
The plans for 2024 reflect the landscape of technology and innovation. They also underscore Thailand and China’s shared commitment to harness innovation’s power for sustainable growth and development. As technology continues to reshape the global landscape, these collaborative efforts are set to make significant contributions across various sectors. Together, these two nations aim to create a powerful technological synergy that promises a brighter and more connected future on the global stage.
This recent meeting between MHESI and MOST marks a promising partnership at the intersection of science, technology, and innovation. With ongoing endeavours in rail technology and technology transfer, as well as forward-looking plans for digital technology and AI in 2024, the collaboration is poised to make significant contributions to the advancement of both Thailand and China. As these two nations combine their strengths, they stand to create a technological synergy that promises sustainable development and a brighter future on the global stage.
In an exciting collaboration between LASALLE College of the Arts (LASALLE) and the Singapore University of Technology and Design (SUTD), the future of electric vehicle (EV) design is undergoing a remarkable transformation. This pioneering effort, a testament to engineering excellence and design innovation, has birthed an avant-garde electric vehicle prototype that is making waves at LASALLE College of the Arts as part of Singapore Design Week.
Led by Nathan Yong, Programme Leader of BA (Hons) Product Design at LASALLE and a recipient of the President’s Design Award, three students from LASALLE, namely Choong Yu Haun, Namjot Kaur, and Joel Yong, joined forces with SUTD’s Electric Vehicle Club (EV Club) to embark on a journey that reimagines the art of electric vehicle design.
At the heart of this transformative project lies the innovative use of 3D printing technology, a disruptive force that is reshaping the automotive landscape. Drawing inspiration from the intricate and efficient forms found in nature, particularly in insects, the collaborative team has pushed the boundaries of design to create a body shell that epitomises speed, agility and a new benchmark for future electric vehicles.
In doing so, they have also made substantial strides towards sustainable transportation design, underscoring their commitment to environmental stewardship and technological advancement.
The result of this remarkable collaboration is the TITHONUS design, crafted by LASALLE students and based on the open-top tandem two-seater electric sports car initially designed and built by SUTD students.
This lightweight chassis houses a quad-motor electric powertrain capable of short 2-second bursts of up to 1,000Nm of torque. With double-wishbone suspension all around and 18-inch wheels regulated by disc brakes, TITHONUS is a testament to the fusion of creativity, engineering acumen, and digitalisation in the pursuit of a sustainable and thrilling automotive future.
LASALLE receives tuition grant support from Singapore’s Ministry of Education and is a founding member of the University of the Arts Singapore. Besides, the partnership between LASALLE and SUTD has not only pushed the boundaries of electric vehicle design but also showcased the transformative power of 3D printing technology and digitalisation in the realm of transportation.
Singapore’s commitment to sustainable mobility is evident in its ambitious goals to reduce carbon emissions and mitigate the impact of climate change. The government’s “Green Plan 2030” outlines a clear roadmap for transforming the country’s transportation sector. At the forefront of this transformation are electric vehicles, which are seen as a pivotal solution to reduce the carbon footprint of the transportation industry.
Digitalisation is the driving force behind Singapore’s electric vehicle revolution. The integration of digital technologies into every facet of the EV ecosystem is unlocking new possibilities and reshaping the way we perceive and use electric vehicles.
Also, central to the success of EVs is a robust charging infrastructure. Digitalisation has enabled the development of a smart charging network across Singapore. EV owners can easily locate charging stations through mobile apps, check availability in real time, and even make reservations. Additionally, predictive analytics help optimise the placement of charging stations based on usage patterns, ensuring convenience for users.
Digitalisation has transformed the way EVs are managed and maintained as advanced telematics systems allow for remote diagnostics, real-time monitoring of vehicle health, and over-the-air software updates. This not only enhances the overall reliability of EVs but also minimises downtime and reduces maintenance costs.
The Ministry of Communication and Information Technology is devising incentives to support the implementation of 5G telecommunications network technology in Indonesia. This step is taken as part of a strategy to optimise the 5G network to enhance internet speed significantly.
Minister of Communication and Information Technology, Budi Arie Setiadi has revealed that the government’s efforts are geared towards encouraging investment in this sector. One specific measure is to incentivise telecommunications operators to encourage them to make large-scale investments. With these incentives in place, operators can avoid making a substantial upfront payment, which can reduce their investment costs.
Budi Arie Setiadi also expressed his belief that internet speed in Indonesia will continue to increase in line with the advancement of digital technology. The Ministry of Communication and Information Technology is committed to making Indonesia one of the top 10 countries in the world in terms of internet speed by implementing a robust 5G network. Therefore, the government will continue to focus on developing the digital infrastructure to support this goal.
In addition, Budi Arie Setiadi emphasised the importance of establishing a strong digital infrastructure. He explained that includes the development of a reliable and extensive 5G network, which will help meet the needs of the public and industries as they navigate the ever-evolving digital era.
“5G in the future will undoubtedly play a pivotal role in shaping not just the telecommunications landscape but also the broader digital ecosystem,” Budi Arie Setiadi elaborated. As the world becomes increasingly interconnected and reliant on high-speed data transmission, Indonesia is positioning itself strategically to harness the potential of 5G technology for its growth and development.
The Ministry of Communication and Information Technology has embarked on a mission to position Indonesia, the world’s fourth most populous country, among the top 10 nations globally regarding 5G network deployment.
“When we discuss speed, it’s a measure relative to other nations, but what truly matters is our global ranking. We employ this benchmark because the world’s pace of internet adoption is not slowing down. Even if our target is to achieve 100 Mbps, if we observe that the global rankings are on the ascent, we remain steadfast in our pursuit,” he expressed.
Furthermore, he also underscored that the government is committed to assessing and crafting strategic initiatives to deliver improved-speed 5G network services. He emphasised that they are poised to collaborate closely with various mobile operators and industry ecosystems to formulate the most effective strategies.
In pursuing high-quality internet network services, the government also remains acutely attuned to the evolving dynamics within the domestic industry.
Budi Arie further highlighted the significance of fostering an industrial ecosystem that enhances quality sustainably and competitively. He said that it is paramount as it will ensure the industry sustains its health and engages in fair competition.
Commercial 5G services are already operational in 49 cities across Indonesia. Furthermore, the development of 5G networks is actively progressing in five super-priority tourist destinations and is being showcased at various international events.
The Minister’s emphasis on global ranking highlights Indonesia’s determination to benchmark itself against international standards. It acknowledges that the digital landscape is dynamic and constantly evolving, and being among the top performers globally clearly indicates staying relevant in the digital age.